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How Are Sweat and Saliva Triggers for Atopic Dermatitis?

For some people with atopic dermatitis (AD), bodily fluids like sweat or excess saliva can act as triggers for the dry, itchy, red skin condition. As a chronic condition, it is important for people living with AD to identify and avoid their personal triggers as much as possible. Flares of AD cause lesions on the skin and intense itching and scratching can lead to infections and lichenification, or thickened skin, which is continuously itchy.1

Infants, atopic dermatitis and drooling

Sixty-five percent of all cases of AD are diagnosed in children before the age of 1. While excess saliva or drooling does not cause AD, it can aggravate the condition, making it worse. Infants often have the red, dry, itchy patches of AD on their cheeks or chin, areas that can be irritated with drooling. During teething, infants have even more drooling, causing a flare of AD. Since drooling cannot be controlled, the best defense against this common trigger of AD in children is effective skin care, including washing the face with a mild soap and moisturizing to create a protective barrier on the skin.1,2

Sweat and atopic dermatitis

The excess moisture on the skin that occurs with sweating can be a trigger for people with AD, causing a flare of symptoms and increasing the itchiness of the affected areas of the skin. In addition, many people with AD have a hypersensitivity to sweat: their bodies respond to the presence of sweat by producing histamine, a chemical that is released by the immune system in response to allergens. Histamine causes inflammation, and while other many allergens can be avoided, such as pet dander or certain foods, sweat is a natural function of the body that cannot be completely eliminated.3

While sweat may trigger AD, sweat also provides a number of healthy benefits, including:

  • Maintaining the skin’s homeostasis, especially the balance of temperature
  • Assisting in the antimicrobial function of the skin to protect against microorganisms like bacteria, virus, and fungi
  • Providing a natural moisturizing effect
  • Helping to regulate the skin surface pH4

Sweat management techniques involve educating people with AD on the important benefits of sweat and encouraging proper skin care. Showering or bathing after sweating, patting the skin dry, and applying a good moisturizer can help protect the skin and reduce the risk of flares of AD. Studies have demonstrated that children with AD have significant improvement in their symptoms if they take showers at school, such as after physical education class.4

Emily Downward | June 2017
  1. Tollefson MM, Bruckner AL. Atopic dermatitis: skin-directed management. Am Acad Pediatrics. 2014 Dec;134(6):e1735-1744. doi: 10.1542/peds.2014-2812.
  2. Giam YC, Hebert AA, Dizon MV, et al. A review on the role of moisturizers for atopic dermatitis. Asia Pacific Allergy. 2016;6(2):120-128. doi:10.5415/apallergy.2016.6.2.120.
  3. Hide M, Tanaka T, Yamamura Y, Koro O, Yamamoto S. IgE-mediated hypersensitivity against human sweat in patients with atopic dermatitis. Acta Derm Venereol. 2002;82:335-340.
  4. Kaneko S, Murota H, Murata S, Katayama I, Morita E. Usefulness of sweat management for patients with adult atopic dermatitis, regardless of sweat allergy: a pilot study. BioMed Research International. 2017;2017:8746745. doi:10.1155/2017/8746745.