A graphic arm taking an injection from someone else.

Dupixent Syringe Injection Tutorial

Are you nervous about self-injecting or having someone else inject your first dose of Dupixent? Fear not! Noreen and Jeff, two AtopicDermatitis.net advocates, have shared the step-by-step process on how to inject Dupixent in the videos below. Jeff has used Dupixent since April of 2018 and Noreen has used it since April of 2019.

Noreen's experience with Dupixent

I started Dupixent in April and genuinely had no idea how I’d be giving myself injections! However, my partner has been administering my shots, which has been a huge sigh of relief for me. Transitioning to an injection every 2 weeks is a bit scary, so I put together a tutorial video to help guide others through the process - it’s actually not that painful and you get into a routine.

How someone else should inject Dupixent

  1. Step 1: Let the syringe sit outside of the fridge for at least 45 minutes
  2. Step 2: After washing your hands, clean the area you are going to inject with an alcohol wipe
  3. Step 3: Take the needle cap off of the syringe right before you are going to inject
  4. Step 4: Hold the syringe at a 45-degree angle, pinch a fold of skin at the site of injection, and take a deep breath
  5. Step 5: Insert the needle completely in the skin and push down the white plunger rod until it’s completely done
  6. Step 6: Remove the needle and take your thumb off the syringe and the plunger retracts
  7. Step 7: Dispose of the used needle and syringe in the sharps collector

How to self-inject Dupixent

  1. Step 1: Remove the Dupixent syringe from your refrigerator and allow it to sit for at least 45 minutes.
  2. Step 2: Grab your syringe, alcohol swab, and sharps container.
  3. Step 3: Make sure the Dupixent is clear in color and is not past the expiration date.
  4. Step 4: After washing your hands, clean the injection site with an alcohol swab. If you’re injecting the medication into your stomach, make sure to cleanse an area that is 2 inches away from your belly button.
  5. Step 5: Remove the needle cap from the syringe.
  6. Step 6: Firmly hold the syringe at a 45-degree angle and pinch a fold of skin at the site of injection with your other hand.
  7. Step 7: Insert the needle completely into your skin and push down the plunger until the medication is completely gone (you’ll hear a little click).
  8. Step 8: Remove the needle and release your thumb from the plunger.
  9. Step 9: Discard the used syringe into your sharps container.
  10. Step 10: Apply a Band-Aid or gauze pad (as needed).

Be sure to speak with your doctor if you have any questions or concerns about administering Dupixent.

Dupixent Discussion: Talk to people about Dupixent for eczema.

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This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The AtopicDermatitis.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

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