Hey - I was offered powerful immunosuppressants a while ago and after lots of thinking decided against it for the very reasons you highlight. Being an asthmatic, I have to be very careful. I've not tried Azathioprine but we all react to certain medications in different ways. When debating whether to go onto new medications, I always weigh up the pros and cons. Hopefully someone can reach out to you who has some experience of this drug. Good luck! Pete, Moderator