Dupixent Question
Hi. I started Dupixent about five weeks ago. My symptoms are clearing up and I'm happy with the results so far, but then this week I flared. I looked back at what I ate over the weekend and I did ingest some possible triggers (sugar, gluten, eggs) but I guess I was surprised to flare while on Dupixent. Anyone else had flares after exposure to known triggers? Does this mean even with Dupixent I need to avoid exposure to things I feel strongly are triggers?
, I have been suffering with pretty severe eczema on most of my body for close to a year now. I go back to the dermatologist tomorrow after three doses across six weeks and my skin is much better, but still itchy and last week I had a flare on my chest and stomach. I had allergy testing earlier in the year and tons of foods came up hot, and my IGE was over 800. I tried eliminating all the foods as best I could, but there wasn't much change until the Dupixent. But a few days before the flare I went a little overboard on a few things that came up allergic on my test -- wheat and eggs. I didn't test for sugar but think it may be an issue and I had a ton of sugar a few days before the flare. I guess I was naive to think I could go on Dupixent and go back to ingesting things that may have caused flares like wheat (gluten) and sugar. The flare seems to have subsided after a few days though. So I'm thinking maybe I did have TSW last week. Dupixent has been working, and about 10 days ago I stopped all steroid creams cold turkey. Then on Mon/Tue last week my chest, stomach and back blew up. I didn;t know if I should go back to steroid cream at that point, but decided not to. Then after a Dupixent injection on Saturday, I cleared up quickly and stopped itching.
I don't think the flare could have been from food. I really didn't have anything that would have caused it. I "cheated" with one tiny chocolate chip cookie a few days before the flare but I can't believe that small amount of sugar or gluten could have done so much damage. I cheated the week before with a whole sleeve of Oreos (10 cookies at once) and I did get a little flare after that the following day. But it could have just been the stress associated with spending two days with my elderly parents. So I don't know what to think.TSW makes the most sense. I'm hoping I stay clear for two weeks post Dupixent because I'd hate to think it just doesn't last long enough between injections and the flare was just the med wearing off.
What do you think? Sound like TSW?
It is truly hard for me to say, especially since I have not seen pictures. It is a possibility if you were a chronic steroid user, but I do hope Dupixent continues to work for you. I am grateful I am on it at the moment. It has taken my flares away at the moment. I am 3 months in. Let's see how it goes for you!
Hi lengutman!
I, too, am on Dupixent. I am grateful that it has been making my skin journey so much more comfortable. I am 2.5 months into this treatment with no flares. However, I think there may be factors to consider for you. 1) What are you taking Dupixent for (TSW, severe eczema, eczema and asthma, etc)? 2) Do you have allergies or just 'triggers' as in, normal things eczema patients are told to avoid?
I know a few others on Dupixent that just have random flares in the beginning, but there is also a side effect that deals with flushing in the face (is that what you are experiencing?)
At the end of the day, we are all different, but sometimes, flares just seem to happen on Dupixent. I hope others are able to comment on their own experience here for you. It's still early stages of Dupixent so give it another month or two 😀 - Briana, Moderator
