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Dupixent Question

Hi. I started Dupixent about five weeks ago. My symptoms are clearing up and I'm happy with the results so far, but then this week I flared. I looked back at what I ate over the weekend and I did ingest some possible triggers (sugar, gluten, eggs) but I guess I was surprised to flare while on Dupixent. Anyone else had flares after exposure to known triggers? Does this mean even with Dupixent I need to avoid exposure to things I feel strongly are triggers?

  1. Dupixent is a patch, just like taking Ozempic for weight loss. If one doesn't sort out the diet, then Ozempic will be a lifelong need. Dupixent helped wonders for me but I had reduced my dosage to about 1/3 the dosing schedule and have been off of it for the past year. There have been flareups but mostly I believe related to

    1) not enough exercise
    2) not enough good sun exposure
    3) not using my NIR 850nm near infrared light unit enough
    4) but primarily, eating too many carbs.

    i am convinced that I am mostly off my Dupixent now and my skin is much better from having cut out all fruit and carbs out of my diet. i am basically on a low carb keto diet now. mostly animal products, canned sardines and low-carb veggies.

    No fruit, no carbs of any kind. i used to love potato chips, and grew up with rice, noodles and pasta. Changing the diet to one that has no carbs is not easy.

  2. I agree Briana, I've been on Dupixent for a year, still got "flare ups" not in the least itchy and dry skin gone.

  3. It is only in the beginning that you get now and then a flare and it is not so itchy. I have been using it for a year and it was a lifesaver!

    1. Hello thanks for asking, I am doing well, and hope you are too!

      Sounds like this period can be filled with lots of feelings as you wait to see what will happen with your dream career! I'm rooting for you that it works out!

      As far as the financial burden brought on by certain medications, I can relate. I have been down this road many times. I can't speak for how healthcare and insurance work in India, but I do know that in Canada and the USA, there are patient support programs that every pharmaceutical company has. These patient support programs are often a great resource. If you haven't already asked your doctor about this, I would encourage you to do so. Additionally, exploring options like crowdfunding, non-profit organizations, and government programs might provide some financial relief. Remember, nobody can advocate for you better than yourself!

      As always, I'm here to offer support in any way I can. Please feel free to check back in if you have any questions or updates you'd like to share.

      Chava B. Wald (Moderator & Contriutor)

    2. the average indian has carbs making up 62 % of the diet. Many indians are vegetarians, which makes this condition worse, including acne on the face. Vegetable oil (used for deep frying and also used in curries) and excess consumption of carbs is the main problem for indian patients, in India and in canada where I know many indian friends.

      I believe changing your diet to more meat (mutton, chicken and fish and using coconut oil, and cutting down the rice, naan and potato will help your skin condition)

  4. , I have been suffering with pretty severe eczema on most of my body for close to a year now. I go back to the dermatologist tomorrow after three doses across six weeks and my skin is much better, but still itchy and last week I had a flare on my chest and stomach. I had allergy testing earlier in the year and tons of foods came up hot, and my IGE was over 800. I tried eliminating all the foods as best I could, but there wasn't much change until the Dupixent. But a few days before the flare I went a little overboard on a few things that came up allergic on my test -- wheat and eggs. I didn't test for sugar but think it may be an issue and I had a ton of sugar a few days before the flare. I guess I was naive to think I could go on Dupixent and go back to ingesting things that may have caused flares like wheat (gluten) and sugar. The flare seems to have subsided after a few days though.

    1. So I'm thinking maybe I did have TSW last week. Dupixent has been working, and about 10 days ago I stopped all steroid creams cold turkey. Then on Mon/Tue last week my chest, stomach and back blew up. I didn;t know if I should go back to steroid cream at that point, but decided not to. Then after a Dupixent injection on Saturday, I cleared up quickly and stopped itching.


      I don't think the flare could have been from food. I really didn't have anything that would have caused it. I "cheated" with one tiny chocolate chip cookie a few days before the flare but I can't believe that small amount of sugar or gluten could have done so much damage. I cheated the week before with a whole sleeve of Oreos (10 cookies at once) and I did get a little flare after that the following day. But it could have just been the stress associated with spending two days with my elderly parents. So I don't know what to think.

      TSW makes the most sense. I'm hoping I stay clear for two weeks post Dupixent because I'd hate to think it just doesn't last long enough between injections and the flare was just the med wearing off.


      What do you think? Sound like TSW?

    2. It is truly hard for me to say, especially since I have not seen pictures. It is a possibility if you were a chronic steroid user, but I do hope Dupixent continues to work for you. I am grateful I am on it at the moment. It has taken my flares away at the moment. I am 3 months in. Let's see how it goes for you!

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